The LGC·SeraCare·KPL (hereinafter referred to as KPL) that XMJ represents is a globally renowned commercial secondary antibody and substrate coloration system producer with a product development experience of over 40 years. It has obtained ISO 13485 quality system certification and its products are stable batch-to-batch with reliable quality, which is highly favored and praised by numerous diagnostic enterprises. The product line of KPL includes cost-effective secondary antibodies, substrate coloration reagents, and immunological support reagents, and is widely used in immunological research, diagnostic reagent development, and clinical testing fields. This article will focus on introducing the immunological support reagent products of KPL.

Immunological testing has extremely important applications in various fields such as medicine and biological research, including disease diagnosis, vaccine development, and drug screening. Accurate and reliable test results are of vital importance for scientific research and clinical practice. Immunoassay support reagents play an indispensable role in the immunological testing process, functioning like the lubricant and stabilizer of a precision instrument, ensuring the smooth, efficient and accurate operation of the entire testing process.

Buffer solutions play a crucial role in maintaining stability in immunological tests. They ensure an appropriate pH range, facilitate the smooth conduct of biochemical processes such as antigen-antibody reactions in a stable environment, and prevent deviations in test results due to pH fluctuations. The KPL brand buffer solutions, with their unique formulation, guarantee the stability of the buffer solutions and are compatible with various testing systems and reagents.

The blocking solution plays a crucial role in immunological testing by pre-binding to the blank sites in the detection system (such as the blank protein binding sites in ELISA plate wells), preventing the adsorption of non-specific proteins and reducing false positive results caused by non-specificity, thereby ensuring the accuracy of the results. Common components of blocking solutions include non-protein-based blockers and protein-based blockers. The KPL brand blocker has high stability and is not easily affected by changes in experimental conditions such as temperature and pH value. Even in complex test samples or high-concentration protein environments, it can effectively prevent non-specific binding and significantly improve the accuracy of the test.

The washing solution is used to remove unbound antigens, antibodies, non-specifically bound proteins and other impurities, reducing background interference and enhancing the contrast between the detection signal and the background, thereby improving the sensitivity and specificity of the detection,during the immunological detection process. The surfactants and salts in the washing solution work synergistically to achieve an effective washing effect, while avoiding damage to the target detection substances. The unique formula of KPL washing agent enables efficient removal of impurities under mild conditions, significantly reducing the background noise in the detection results. KPL washing solution is available in concentrated form, allowing for rapid preparation of the desired concentration according to experimental requirements.

The stop solution terminates the enzymatic reaction during the immunological detection process by altering the reaction conditions (such as changing the pH value), ensuring that the generation of reaction products is interrupted at a specific moment, so as to accurately measure the amount of reactants and thereby calculate the concentration of the analyte. The KPL termination solution can quickly terminate the reaction in a short period of time and maintain a stable state, thus ensuring the reliability of the detection results.

Stabilizers are used to maintain the stability and activity of enzyme markers (such as horseradish peroxidase HRP or alkaline phosphatase AP), thereby ensuring the accuracy and reproducibility of experimental results. Commonly used stabilizers include glycerol, BSA, diethanolamine, and other commercial products. KPL stabilizers are ready-to-use solutions and are widely used in applications that require enzyme markers, such as ELISA, Western blot (WB), and immunohistochemistry (IHC).

An enhancer is a reagent used to increase the detection sensitivity and signal intensity. During the WB experiment, it can enhance the antibody signal that binds to the target protein on the membrane, which helps to improve the signal-to-noise ratio of low-quality and low-affinity antibodies, reduce background noise, and make the WB results clearer.

Fluorescence mounting media is commonly used in immunological experiments such as immunofluorescence (IF), fluorescence in situ hybridization (FISH), and flow cytometry, to protect samples from external environmental interference, reduce photobleaching, and enhance signal stability. KPL's fluorescent mounting media is a glycerol-based solution based on immunofluorescence microscopes. Its unique formulation contains inhibitors that can significantly slow down the photobleaching process of fluorescent markers such as fluorescein and rhodamine, and can also be used as a diluent for fluorescently labeled conjugates.

KPL (Kinetic Plasmonics Laboratories) is a company with a profound history and an outstanding reputation in the field of biological sciences. As one of the world’s early biotech companies to commercialize affinity-purified secondary antibodies, KPL has laid a solid foundation for its development by virtue of its pioneering position in this field. In addition, KPL is also one of the world’s leading manufacturers of secondary antibodies and chromogenic substrate systems, boasting nearly 40 years of experience in product R&D, as well as a wealth of professional knowledge and technical capabilities accumulated over the years. The company has obtained ISO 13485 quality management system certification, which ensures that all its products have minimal batch-to-batch variation and reliable quality. Characterized by high purity, high sensitivity, and an excellent signal-to-noise ratio (strong signal with low background), KPL’s products are highly trusted by researchers and diagnostic enterprises.

In 2013, KPL was acquired by SeraCare, a supplier of in vitro diagnostic (IVD) reagents, further consolidating its leading position in the industry. Founded in 1984, SeraCare is a major partner for global IVD manufacturers and clinical laboratories, and became part of the LGC Group in 2018. As the exclusive distributor of the LGC·SeraCare·KPL brand in China, Beijing XMJ Biotechnology Co., Ltd. is committed to promoting KPL’s high-quality products in the Chinese market and providing domestic researchers with premium products and professional services.

XMJ is the agent of LGC·Seracare·KPL brands in China. dedicated to promoting the excellent products of KPL in China and providing high-quality products and professional services to the vast number of scientific researchers in the country.

If you are interested in the products, please feel free to call the national customer service hotline of XMJ at 400-050-4006 or visit the official website: m.emergexcelerate.com to learn more information.